Sunday, November 18, 2018

The Human Cell and Its Organelles With Details

Cell is the structural and functional unit of a living body. Cell is the smallest unit of human body.
Divided the cell into three parts-
  1. Plasma membrane
  2. Cytoplasm
  3. Nucleus
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Human healthy Cell Or Animal Cell


Plasma membrane

Every cell has flexible outer surface that separating the internal environment from the external environment. Various channels and selective barrier are present on plasma membrane that regulate the flow of material into and out of a cell.
Plasma membrane compose with double layer of phospholipids and proteins. 
  


Cytoplasm

Cytoplasm is consist of all the cellular content between the plasma membrane and nucleusCytoplasm has two components
  1. Cytosol
  2. Organelles
  • Cytosol : The fluid portion of the cytoplasm, which contains water, dissolved solutes and suspended particles.
  • Organelles  (Little organ) : Many tiny organs are suspended in cytoplasm. Each organ has particular shape and function. These organs are mitochondria, endoplasmic reticulum, golgi apparatus, ribosomes, lysosomes, centrosome, vesicles and peroxisomes.


Mitochondria 

Mitochondria referred as a power house of cell because they generate most of energy (in the form adenosine triphosphate -ATP).  A cell may have large number of mitochondriaMitochondria consist of an outer membrane and inner membraneBetween the membrane, fluid is present. Fluid is filled in mitochondria cavity, called mitochondrial matrix.
                      Tubular like structures are form in inner mitochondrial membrane that know as mitochondrial cristae. Some ribosomes are present on mitochondrial cristae and some ribosomes are free in mitochondrial matrix.

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Mitochondria 


Function of mitochondria

  • Supplying cellular energy
  • Kreb’s cycle occur in mitochondria
  • Mitochondria maintaining control of the cell cycle and cell growth
  • Regulate cellular metabolism
  • Mitochondria play a important role in apoptosis (programmed of cell death)
  • Calcium ions are stored in mitochondria
  • Steroid synthesis takes place in mitochondria
  • Mitochondria is sites of several metabolic reactions 
 Metabolic reaction in outer mitochondrial membrane :- 
                                             Oxidation of epinephrine
                                                         Degradation of tryptophan           
                                                         Elongation of fatty acids
Metabolic reaction in inner mitochondrial membrane :- 
                                             Oxidation of phosphorylation
Metabolic reaction in mitochondrial matrix :- 
                                             Kreb’s cycle
                                                  Beta oxidation
                                        Detoxification of ammonia in urea cycle
                                        Storage of calcium ion 

Respiratory system - its Structure & Function


Endoplasmic reticulum(ER) 

Endoplasmic reticulum is most extensive cell organelle present in the cytoplasm. Endoplasmic reticulum is tubular like structure. Various enzymes are synthesized in endoplasmic reticulum

Endoplasmic reticulum is two types:
  • Smooth endoplasmic reticulum: Tubular like structure. Ribosomes are absent. Smooth endoplasmic reticulum also known as agranular endoplasmic reticulum.
  • Rough endoplasmic reticulum: Tubular like structure. Ribosomes are present on the surface of tubular. This type of ER also involve in protein synthesis. Rough endoplasmic reticulum is also known as granular endoplasmic reticulum.
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Endoplasmic Reticulum 


Golgi Apparatus

The golgi apparatus is a major collection and dispatch station of protein products, received from the endoplasmic reticulum. Protein synthesis occur in endoplasmic reticulum, pack into vesicles and then fused into golgi complex.      

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Golgi apparatus


Ribosome

Ribosomes are tiny structure. Ribosomes are types 70S and 80S, both type of ribosomes are consist with two subunits
  • 70s ribosome : Two subunit: 50s and 30s.
  • 80s ribosome : Two subunit: 60s and 40s.




Some ribosomes are attached to the surface of endoplasmic reticulum. Free ribosomes are synthesize proteins used in cytosol.
Ribosomes are also located within mitochondria, where they synthesize mitochondrial proteinRibosomes main function is translation in which mRNA convert into protein.

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Ribosome 


Lysosome

(Lyso means dissolving and somes means bodies). Lysosomes can contain as many as 60 kinds of powerful digestive enzyme and hydrolytic enzyme that can break down a wide variety of molecules. Lysosome can engulf another organelles, digest it and return the digested components to the cytosol for reuse.


Centrosome

Centrosome are partially present in animal cell. Centrosome is located near the nucleus. During cell division centrosomes replicate so that succeeding generation of cells have capacity for cell division.


Peroxisomes

Similar structure like lysosome. Peroxisomes contains several oxidases enzymes that oxidize (remove hydrogen atom from molecules).

Vesicle

Vesicles are involved in many metabolism, transport and temporary storage of enzyme and food. Vesicles from naturally during the processes of secretion, uptake and transport of compound with in the cytoplasm.   

Microsomes

These are small and sac like structure present in cytoplasm of cell. Endoplasmic reticulum breakdown in fragments, these fragments forms microsomes. When a tissue homogenate at very high speed (10,000 rmp), they can separated. 
                          Microsomes contain ribosomes. Ribosome involve in synthesis of protein. Microsomes also contain granular matrix, that contain two enzymes – oxidases and catalases. Microsomes are not present in normal and healthy cells.

Function of Microsomes
  • Oxidases enzyme – This enzyme help to generate hydrogen peroxide.
  • Catalases enzyme – This enzyme convert hydrogen peroxide to water.

Nucleus

Large organelle that houses most of a cell’s DNA. A single molecule of DNA associated with several proteins and contains thousands of hereditary units called genes. Genes control cellular structure and function.
  • Nucleus is spherical or oval shaped structure.
  • Nucleus is consisting with lipid bilayer.
  • Nucleus pores control the movement of substances between the cytoplasm and nucleus by diffusion.

Functions of Cell

  • Ingestion
  • Growth and repair
  • Metabolism         
                         Anabolism 
                        Catabolism 
  • Respiration
  • Excretion
  • Irritability and conductivity
  • Reproduction 

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