MCQ on ANTIPROTOZOAL AND ANTHELMINTIC DRUGS

1. Tick the drug used for malaria chemoprophylaxis and treatment:

a) Chloroquine

b) Quinidine

c) Quinine

d) Sulfonamides

Ans: (a)

2. Tick the drug used for amoebiasis treatment:

a) Nitrofurantoin

b) Iodoquinol

c) Pyrazinamide

d) Mefloquine

Ans: (b)

3. Tick the drug used for trichomoniasis treatment:

a) Metronidazole

b) Suramin

c) Pyrimethamine

d) Tetracycline

Ans: (a)

4. Tick the drug used for toxoplasmosis treatment:

a) Chloroquine

b) Tetracyclin

c) Suramin

d) Pyrimethamine

Ans: (d)

5. Tick the drug used for balantidiasis treatment::

a) Azitromycin

b) Tetracycline

c) Quinine

d) Trimethoprim

Ans: (b)

6. Tick the drug used for leishmaniasis treatment:

a) Pyrimethamine

b) Albendazole

c) Sodium stibogluconate

d) Tinidazole

Ans: (c)

7. Tick the antimalarial drug belonging to 8-aminoquinoline derivatives:

a) Doxycycline

b) Quinidine

c) Primaquine

d) Chloroquine

Ans: (c)

8. All of the following antimalarial drugs are 4-quinoline derivatives, EXCEPT:

a) Chloroquine

b) Mefloquine

c) Primaquine

d) Amodiaquine

Ans: (c)

9. Tick the antimalarial drug belonging to pyrimidine derivatives:

a) Mefloquine

b) Pyrimethamine

c) Quinidine

d) Chloroquine

Ans: (b)

10. Tick the drug used for trypanosomosis treatment:

a) Melarsoprol

b) Metronidazole

c) Tetracyclin

d) Quinidine

Ans: (a)

11. Tick the antimalarial drug having a gametocidal effect:

a) Mefloquine

b) Primaquine

c) Doxycycline

d) Sulfonamides

Ans: (b)

12. All of the following antimalarial drugs influence blood schizonts, EXCEPT:

a) Mefloquine

b) Chloroquine

c) Primaquine

d) Quinidine

Ans: (c)

13. Tick the antimalarial drug influencing tissue schisonts:

a) Mefloquine

b) Chloroquine

c) Quinidine

d) Primaquine

Ans: (d)

14. Tick the group of antibiotics having an antimalarial effect:

a) Aminoglycosides

b) Tetracyclins

c) Carbapenems

d) Penicillins

Ans: (b)

15. Tick the amebecide drug for the treatment of an asymptomatic intestinal form of amebiasis:

a) Chloroquine

b) Diloxanide

c) Emetine

d) Doxycycline

Ans: (b)

16. Tick the drugs for the treatment of an intestinal form of amebiasis:

a) Metronidazole and diloxanide

b) Diloxanide and streptomycin

c) Diloxanide and Iodoquinol

d) Emetine and metronidazole

Ans: (a)

17. Tick the drug for the treatment of a hepatic form of amebiasis:

a) Diloxanide or iodoquinol

b) Tetracycline or doxycycline

c) Metronidazole or emetine

d) Erythromycin or azitromycin

Ans: (c)

18. Tick the luminal amebecide drug:

a) Metronidazole

b) Emetine

c) Doxycycline

d) Diloxanide

Ans: (d)

19. Tick the drug of choice for the treatment of extraluminal amebiasis:

a) Iodoquinol

b) Metronidazole

c) Diloxanide

d) Tetracycline

Ans: (b)

20. Tick the drug, blocking acetylcholine transmission at the myoneural junction of helminthes:

a) Levamisole

b) Mebendazole

c) Piperazine

d) Niclosamide

Ans: (c)

21. Tick niclosamide mechanism of action:

a) Increasing cell membrane permeability for calcium, resulting in paralysis, dislodgement and death of helminthes

b) Blocking acetylcholine transmission at the myoneural junction and paralysis of helminthes

c) Inhibiting microtubule synthesis in helminthes and irreversible impairment of glucose uptake

d) Inhibiting oxidative phosphorylation in some species of helminthes

Ans: (d)

22. Tick praziquantel mechanism of action:

a) Blocking acetylcholine transmission at the myoneural junction and paralysis of helminthes

b) Inhibiting microtubule synthesis in helminthes and irreversible impairment of glucose uptake

c) Increasing cell membrane permeability for calcium, resulting in paralysis, dislodgement and death of helminthes

d) Inhibiting oxidative phosphorylation in some species of helminthes

Ans: (c)

23. Tick piperazine mechanism of action:

a) Inhibiting microtubule synthesis in helminthes and irreversible impairment of glucose uptake

b) Blocking acetylcholine transmission at the myoneural junction and paralysis of helminthes

c) Inhibiting oxidative phosphorylation in some species of helminthes

d) Increasing cell membrane permeability for calcium, resulting in paralysis, dislodgement and death of helminthes

Ans: (b)

24. Tick the drug, a salicylamide derivative:

a) Praziquantel

b) Piperazine

c) Mebendazole

d) Niclosamide

Ans: (d)

25. Tick mebendazole mechanism of action:

a) Inhibiting oxidative phosphorylation in some species of helminthes

b) Increasing cell membrane permeability for calcium, resulting in paralysis, dislodgement and death of helminthes

c) Inhibiting microtubule synthesis in helminthes and irreversible impairment of glucose uptake

d) Blocking acetylcholine transmission at the myoneural junction and paralysis of helminthes

Ans: (c)

26. Tick the drug, inhibiting oxidative phosphorylation in some species of helminthes:

a) Niclosamide

b) Piperazine

c) Praziquantel

d) Mebendazole

Ans: (a)

27. Tick the drug for neurocysticercosis treatment:

a) Praziquantel

b) Pyrantel

c) Piperazine

d) Bithionol

Ans: (a)

28. Tick the drug for nematodosis (roundworm invasion) treatment:

a) Niclosamide

b) Praziquantel

c) Bithionol

d) Pyrantel

Ans: (d)

29. Tick the drug for cestodosis (tapeworm invasion) treatment:

a) Piperazine

b) Praziquantel

c) Pyrantel

d) Ivermectin

Ans: (b)

30. Tick the drug for trematodosis (fluke invasion) treatment:

a) Bithionol

b) Ivermectin

c) Pyrantel

d) Metronidazole

Ans: (a)

31. Tick the drug, a benzimidazole derivative:

a) Praziquantel

b) Mebendazole

c) Suramin

d) Pyrantel

Ans: (b)

32. Tick the broad spectrum drug for cestodosis, trematodosis and cycticercosis treatment:

a) Piperazine

b) Ivermectine

c) Praziquantel

d) Pyrantel

Ans: (c)

33. Tick the drug for ascaridosis and enterobiosis treatment:

a) Bithionol

b) Pyrantel

c) Praziquantel

d) Suramin

Ans: (b)

34. Tick the drug for strongiloidosis treatment:

a) Niclosamide

b) Praziquantel

c) Bithionol

d) Ivermectin

Ans: (d)

35. Tick the drug for echinococcosis treatment:

a) Suramin

b) Mebendazole or Albendazole

c) Piperazine

d) Iodoquinol

Ans: (b)

MCQ on ANTIPROTOZOAL AND ANTHELMINTIC DRUGS