Yes, dexamethasone has been on the WHO Model List of Essential Medicines (EML) since 1977 for several indications in multiple formulations. Since 2013, dexamethasone (Injectable formulation) has been indicated for respiratory distress syndrome in new-borns. Prednisolone is also on the EML and was included in 1984.
Dexamethasone and prednisolone are included on the EML for the following indications:- allergic or hypersensitivity conditions, without further specifying the type
- pain and oedema due to malignancy in palliative care
- nausea and vomiting,
- as part of treatment protocols for some blood tissue cancers.
These indications are broad and can also include cytokine-related lung injury and as prevention or treatment of acute respiratory distress syndrome (ARDS) associated with severe acute respiratory infections (i.e. viral pneumonia). Both medicines are also recommended in children.
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