Among the leukocytes in bone marrow are cells that combat infections. A bone marrow transplant is the transfer of bone marrow from a donor to a recipient. The donor marrow must be very closely matched to that of the recipient.
In the procedure, donor marrow is aspirated from the hip bones, mixed with heparin (an anticoagulant), and then passed through screens.
The suspension of bone marrow cells is treated to remove T cells and injected into a vein. The cells in the suspension pass through the lungs, enter the general circulation, and reseed and grow in the marrow cavities of the recipient's bones.
Bone marrow transplants have been used to treat aplastic anemia, certain types of leukemia and severe combined immunodeficiency disease (SCID), an inherited deficiency of infection fighting blood cells.
The technique is also being used to treat Hodgkin's disease, non-Hodgkin's lymphoma, Tallahassee, multiple myeloma, sickle-cell anemia (SCA) and hemolytic anemia.
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