Cushing's Syndrome is a hypersecretion of glucocorticoids, especially cortisol and cortisone. The condition is characterized by the redistribution of fat.
The result is spindly arms and legs, due to catabolism of muscle proteins, accompanied by a rounded "moon face," "buffalo hump" on the back, and pendulous (hanging) abdomen.
Facial skin is flushed and the skin covering the abdomen develops stretch mark (striae). The individual also bruises easily, and wound healing is poor.
Other symptoms include hypertension, increased susceptibility to infection, decreased resistance to stress and mood swings.
The most common cause of a cushinoid appearance is the administration of a glucocorticoid such as prednisone to a transplant recipient or to treat asthma or chronic inflammatory disorders.
0 comments:
Post a Comment