Hodgkin's disease (HD) is a form of cancer, usually arising in lymph nodes, the cause of which is unknown. It may, however, arise from a combination of genetic predisposition, disturbance of the immune system, and the Epstein - Barr virus.
Initially, the disease is characterized by a painless, non-tender enlargement of one or more lymph nodes, most commonly in the neck but occasionally in the axilla, inguinal or femoral region.
Some patients also have an unexplained and persistent fever and/or night sweats. Fatigue and weight loss are also associated complaints, as is pruritus (itching).
Treatment consists of radiation therapy, chemotherapy and bone marrow transplants. Hodgkin's disease is considered to be a curable malignancy.
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