Negative Feedback Mechanism

Two type of feedback mechanism-

 

1. Positive feedback mechanism
2. Negative feedback mechanism

Here we discuss Negative feedback mechanism-

Inn a feedback system, the hormone secreting tissue continuously receives information (feedback) in the form of chemical signals concerning the cellular process it controls. If condition change, the tissue can act upon the information and adjust its rate of secretion. 

Commonly the control of hormonal secretions involves a negative feedback mechanism.

In such system, an endocrine gland is sensitive to the concentration of a substance it regulates or to the concentration of a product of a process it regulates. whenever this concentration reaches a certain level, the endocrine gland is inhibited (a negative effect), and its secretory activity decreases. 

Then, as the concentration of its hormone drops, the concentration of the regulated substance drops too, and the inhibition on the gland is released. When the gland is no longer inhibited, it begins to secrete its hormone again.

As a result of such negative feed back systems, the concentrations of some hormones remain relatively stable, although they may fluctuate within normal range.