Sunday, May 9, 2021

Partial Agonists

A partial agonist behaves like an agonist under some conditions and acts like an antagonist under different conditions. The drug butorphanol (Stadol) is an example of a partial agonist. Partial agonists behave like antagonists in the presence of a high concentration of a full agonist or when administered after recent exposure to high concentrations of an agonist.

Related Posts:

  • First Pass EffectOrally administered drugs must pass into the hepatoportal circulation (liver) before entering the general circulation. The first-pass effect is a proc… Read More
  • Inverse AgonistsInverse agonists are drugs that have affinity at the receptor site but produce opposite actions (turn “off” a receptor that is activated or turn … Read More
  • AgonistsAn agonist is a drug that binds to and activates the receptor site, eliciting a cellular response. Agonist binding may activate a receptor that was re… Read More
  • Glucosuria or Glycosuria The sodium-glucose symporters can reclaim about 300mg glucose/min. If glomerular filteration is normal, the renal threshold for glucose is a plas… Read More
  • Strychnine Poisoning The importance of inhibitory neurons can be appreciated by observing what happens when normal inhibition is blocked.Normally, inhibitory neurons in th… Read More

0 comments:

Post a Comment