Thursday, June 17, 2021

MCQ on enzyme - Biochemistry

1) What is the count of genes that determine the synthesis of one enzyme?

(a) One

(b) Four

(c) Eight

(d) Sixteen

Answer: (a)


2) Macromolecule chitin is

(a) a simple polysaccharide

(b) sulphur containing polysaccharide

(c) phosphorous containing polysaccharide

(d) nitrogen containing polysaccharide

Answer: (d)


3) Ribozymes are 

(a) RNA acting as enzymes

(b) Ribose sugar acting as enzyme 

(c) Antibodies acting as enzymes 

(d) Protein acting as enzyme 

Answer: (a)


4) Tryptophan synthetase of E.coli, a typical bifunctional oligomeric enzyme consists of

(a) a protein A and one subunit A

(b) a protein designated A

(c) two proteins designated A and B

(d) a protein designated B

Answer: (c)


5) Holoenzyme is made of

 (a) Apoenzyme and Zymogen 

(b) Apoenzyme and Co-enzyme 

(c) Co-enzyme and Prosthetic group 

(d) Prosthetic group and Co-factor

Answer: (b)


6) Enzyme-driven metabolic pathways can be made more efficient by

(a) grouping enzymes into multienzyme free-floating complexes

(b) concentrating enzymes with specific cellular compartments

(c) fixing enzymes into membranes so they are adjacent to each other

(d) all of these

Answer: (d)


7) Abzymes are 

(a) Proteins

 (b) DNAs 

(c) RNAs 

(d) Antibodies 

Answer: (d)


8) Which of the following is not a co-enzyme

(a) NAD 

(b) NADP 

(c) FAD 

(d) Mn++ 

Answer: (d)


9) Which enzymes do not require co-enzymes for their activity ? 

(a) The extracellular enzymes

(b) The intracellular Enzymes 

(c) The mitochondrial enzymes 

(d) The Proenzymes 

Answer: (a)


10) This enzyme was first isolated and purified in the form of crystals

(a) Urease

(b) pepsin

(c) Amylase

(d) Ribonuclease

Answer: (a)


11) What are ribozymes ? 

(a) RNA acting as enzymes 

(b) Protein acting as enzymes 

(c) Ribose sugar acting as enzymes 

(d) Antibodies acting as enzymes 

Answer: (a)


12) Activity of allosteric enzymes are influenced by 

(a) Allosteric modulators

 (b) Allosteric site 

(c) Catalytic site 

(d) None of the above 

Answer: (a)


13) Feed back inhibition means

(a) Initial product inhibition 

(b) End Product inhibition

(c) Enzymatic induction 

(d) None of the above

Answer: (b)


14) In competitive inhibition, inhibitors bears a close structural similarity with the 

(a) Co-enzyme 

(b) Co-factor 

(c) Prosthetic group 

(d) Substrate 

Answer: (d)


15) With regards to enzyme action, this statement is incorrect

(a) Malonate is a competitive inhibitor of succinic dehydrogenase

(b) the substrate binds with the enzyme at its active site

(c) the non-competitve inhibitor binds the enzyme at a site distinct from that binding the substrate

(d) addition of a lot of succinates does not reverse the inhibition of succinic dehydrogenase by malonate

Answer: (d)


16) Enzyme acts best at a particular temperature called 

(a)  Catalytic Temperature 

(b) At normal Body temperature 

(c) Optimum temperature 

(d) None of the above 

Answer: (c)


17) “Ping Pong” reaction is the other name for 

(a) Single-substrate reaction 

(b) Single-displacement bi-substrate reaction 

(c) Double-displacement bi-substrate reaction

 (d) Lysine 

Answer: (c)


18) Uncatalyzed reaction shows ______________ activation energy 

(a) Lower 

(b) Higher

(c) Moderate 

(d) Optimum

Answer: (b)


19) In alcoholism, this enzyme is elevated

(a) acid phosphatase

(b) hepatitis

(c) serum glutamate pyruvate transaminase

(d) glutamyl transpeptidase

Answer: (d)


20) Lock and Key model is also known as 

(a) Template model

(b) Induced fit model 

(c) Khosland’s Model 

(d) Enzyme-substrate interaction model 

Answer: (a)


21) Which bond is not associated with Enzyme-substrate interaction – 

(a) Hydrogen bonds 

(b) Ionic bonds 

(c) Di-sulfide bonds

(d) Van deer Waal’s force of attraction 

Answer: (c)


22) Which of the following statement is incorrect 

(a) Enzymes are protein in nature 

(b) Enzymes are colloidal in nature 

(c) Enzymes are thermolabile

(d) Enzymes are inorganic catalyst

Answer: (d)


23) Apoenzymes dissociates from co-enzymes due to 

(a) Change in pH 

(b) Change in temperature 

(c) Change in substrate concentration 

(d) Change in inhibitor concentration 

Answer: (a)


24) This statement about enzymes is true

(a) enzymes accelerate reactions by lowering the activation energy

(b) enzymes are proteins whose three-dimensional form is key to their function

(c) enzymes do not alter the overall change in free energy for a reaction

(d) all of these

Answer: (d)


25) Which of the following enzyme inhibitions shows decreased Km Value ? 

(a) Competitive inhibition 

(b) Un-competitive inhibition 

(c) Non-competitive inhibition 

(d) Feed back inhibition

Answer: (a)


26) Reversible covalent modification involves 

(a) Activation of proenzymes

(b) Inhibition of proenzymes 

(c) Denaturation of proenzymes 

(d) None of the above

Answer: (a)


27) The nature of an enzyme is

(a) Lipid

(b) Vitamin

(c) Carbohydrate

(d) Protein

Answer: (d)


28) The enzyme COX-1 is vital for human health in this way:

(a) it is a chemical derivative of aspirin

(b) catalyzes the hormone-production which maintains the stomach lining

(c) critical for the biosynthesis of DNA

(d) helps in the transportation of carbon dioxide in the blood

Answer: (b)

MCQ-on-enzyme-Biochemistry
MCQ on enzyme - Biochemistry 


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